In this innovative “purpose-per-seat” science and R&D program, groups of EarthLoop astronauts will be paired with students and scientists, actively participating in and facilitating their pre-selected research and development projects. This direct astronaut involvement provides invaluable mentorship and real-time operational support for a diverse range of experiments, spanning fields from biology and materials science to fluid dynamics and technology demonstrations. By integrating astronauts directly with scientific and R&D endeavors, TSI aims to accelerate scientific discovery, inspire the next generation of STEM professionals, and maximize the utilization of the unique microgravity environment offered by the EarthLoop mission profile.